Integrative Oncology

Understanding IV Therapy in Cancer and Alternative Medicine Approaches to Cancer

At LA Regenerative , we are committed to providing impactful, evidence-driven health and wellness guidance. In response to the growing interest in IV therapy, we emphasize informed decision-making based on current scientific evidence. Dr. Lauren Petrovich's advanced specialized training and meticulously developed IV therapy protocols, designed to complement conventional cancer treatments, represent a unique and highly specialized functional medicine approach, available only within a limited number of expert clinics

Here's what you need to know:

Alternative Cancer Therapy is a personal individualized choice and can be done as a standalone Cancer Therapy in Individuals choosing to forgo Conventional treatments of Chemotherapy, Radiation or Surgery. It can also be done as an Adjunctive Therapy to Improve Response to Chemotherapy and Radiation as well as offset many of the side effects associated with standard therapy and improve quality of life while going through conventional cancer treatments.

Ascorbic Acid/Vitamin C as a mainstay of treatment

Very high dose Vitamin C as a therapeutic agent for cancer was first studied by Linus Pauling, a Nobel Prize-winning chemist, in 1970s-1980s. He concluded that very high doses of vitamin C was toxic to cancer cells, as well as improved cancer patient survival and improved patient quality of life

How Does Vitamin C Kill Cancer Cells?

It is well known that Vitamin C is a potent antioxidant that has many health benefits to the immune system, cardiac health, eye health and even reducing skin wrinkles. What many people are not aware of, is that high-dose IV Vitamin C has shown to be cytotoxic to cancer and kill cancer cells.

At Very high doses, only achieved through IV administration, Vitamin C converts from an antioxidant to a pro-oxidative agent. When this occurs, Ascorbic Acid(Vitamin C) generates hydrogen peroxide in the body. Normal healthy cells have the capacity to neutralize hydrogen peroxide whereas cancer cells do not have the enzyme that can do this and therefore causes peroxidative damage to cancer cells only and ends in cancer cell lysis. These Tumor-toxic doses can only be achieved through IV administration.

PubMed Research databases, a government research database, contains over 50,000 studies in support of these findings.

Ascorbic Acid in addition to optimal levels of Vitamin D, Zinc and other natural compounds have shown to improve outcomes, mitigate symptoms and improve overall quality of life.

Resources

15 Signs and Symptoms of Vitamin C Deficiency

https://www.healthline.com/nutrition/vitamin-c-deficiency-symptoms?utm_medium=email&utm_source=email-share&utm_campaign=social-sharebar-referred-desktop

20-Year Risks of Breast-Cancer Recurrence After Stopping Endocrine Therapy at 5 Years

https://pubmed.ncbi.nlm.nih.gov/29117498/

A Convenient Method for Measuring Blood Ascorbate Concentrations in Patients Receiving High-Dose Intravenous Ascorbate

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3725640/

A Randomized Trial of Ascorbic Acid in Polyposis Coli

https://pubmed.ncbi.nlm.nih.gov/7049351/

Actual growth rate and tumour cell proliferation in human pulmonary neoplasms

https://www.nature.com/articles/bjc1984181

Antioxidants and Other Nutrients Do Not Interfere With Chemotherapy or Radiation Therapy and Can Increase Kill and Increase Survival, Part 2

https://pubmed.ncbi.nlm.nih.gov/17405678/

Antioxidants in cardiovascular therapy: panacea or false hope?

https://www.frontiersin.org/articles/10.3389/fcvm.2015.00029/full

Ascorbic acid and cancer: a review

https://pubmed.ncbi.nlm.nih.gov/371790/

Ascorbic Acid and Its Clinical Role in Orthopaedic Surgery

https://pubmed.ncbi.nlm.nih.gov/30777823/

Ascorbic acid: chemistry, biology and the treatment of cancer

https://pubmed.ncbi.nlm.nih.gov/22728050/

Ascorbic-acid Treatment for Progressive Bone Metastases After Radiotherapy: A Pilot Study

https://pubmed.ncbi.nlm.nih.gov/25362213/

Chemoprevention of Colorectal Neoplasms. Ascorbic Acid and Beta-Carotene

https://pubmed.ncbi.nlm.nih.gov/3789912/

Chemotherapy Use, Performance Status, and Quality of Life at the End of Life

https://pubmed.ncbi.nlm.nih.gov/26203912/

Dietary Vitamins A and C and Lung Cancer Risk in Louisiana

https://pubmed.ncbi.nlm.nih.gov/3179940/

Effect of High-dose Vitamin C Combined With Anti-cancer Treatment on Breast Cancer Cells

https://pubmed.ncbi.nlm.nih.gov/30711954/

Effects of N-acetyl-L-cysteine and Ascorbic Acid on Mutagen-Induced Chromosomal Sensitivity in Patients With Head and Neck Cancers

https://pubmed.ncbi.nlm.nih.gov/1719835/

ESTIMATES OF BREAST CANCER GROWTH RATE FROM MAMMOGRAMS AND ITS RELATION TO TUMOUR CHARACTERISTICS

https://pubmed.ncbi.nlm.nih.gov/26410768/

Evaluation and clinical comparison studies on liposomal and non-liposomal ascorbic acid (vitamin C) and their enhanced bioavailability

https://pubmed.ncbi.nlm.nih.gov/32901526/

Feasibility of Vitamin C in the Treatment of Post Viral Fatigue with Focus on Long COVID, Based on a Systematic Review of IV Vitamin C on Fatigue

https://pubmed.ncbi.nlm.nih.gov/33807280/

Growth Rate of Small Lung Cancers Detected on Mass CT Screening

https://pubmed.ncbi.nlm.nih.gov/11205667/

Harm of IV High-Dose Vitamin C Therapy in Adult Patients: A Scoping Review

https://pubmed.ncbi.nlm.nih.gov/32404636/

High-dose intravenous vitamin C combined with cytotoxic chemotherapy in patients with advanced cancer: a phase I-II clinical trial

https://pubmed.ncbi.nlm.nih.gov/25848948/

High-dose Parenteral Ascorbate Enhanced Chemosensitivity of Ovarian Cancer and Reduced Toxicity of Chemotherapy

https://pubmed.ncbi.nlm.nih.gov/24500406/

High-dose Vitamin C (Ascorbic Acid) Therapy in the Treatment of Patients With Advanced Cancer

https://pubmed.ncbi.nlm.nih.gov/19414313/

High-dose vitamin C proves safe and well-tolerated in brain and lung cancer trials

https://uihc.org/news/high-dose-vitamin-c-proves-safe-and-well-tolerated-brain-and-lung-cancer-trials

Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study

https://pubmed.ncbi.nlm.nih.gov/27940189/

Impact of Intravenous Vitamin C Administration in Reducing Severity of Symptoms in Breast Cancer Patients During Treatment

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8177022/

Incidence and patterns of late recurrences in colon cancer patients

https://onlinelibrary.wiley.com/doi/pdf/10.1002/ijc.29578

Inhibiting Effect of Ascorbic Acid on the Growth of Human Mammary Tumor Xenografts

https://pubmed.ncbi.nlm.nih.gov/1962582/

Intake of Vegetables, Fruits, Beta-Carotene, Vitamin C and Vitamin Supplements and Cancer Incidence Among the Elderly: A Prospective Study

https://pubmed.ncbi.nlm.nih.gov/1419605/

Intravenous Ascorbic Acid Infusion Improves Myocardial Perfusion Grade During Elective Percutaneous Coronary Intervention: Relationship With Oxidative Stress Markers

https://pubmed.ncbi.nlm.nih.gov/20170881/

Intravenous Vitamin C and Cancer: A Systematic Review

https://pubmed.ncbi.nlm.nih.gov/24867961/

Intravenous Vitamin C for Cancer Therapy – Identifying the Current Gaps in Our Knowledge

https://www.frontiersin.org/articles/10.3389/fphys.2018.01182/full

Intravenous vitamin C in the supportive care of cancer patients: a review and rational approach

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5927785/

Intravenous vitamin C in the treatment of shingles: results of a multicenter prospective cohort study.

http://centerhealingarts.com/treatment-programs/iv-therapy-nutrition-chelation/intravenous-vitamin-c-treatment-shingles-results-multicenter-prospective-cohort-study/

Intravenously administered vitamin C as cancer therapy: three cases

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1405876/

Long-Term Risk of Skin Cancer Among Childhood Cancer Survivors: A DCOG-LATER Cohort Study

https://academic.oup.com/jnci/article-abstract/111/8/845/5364730

Longitudinal Follow-Up of Adult Survivors of Ewing Sarcoma: A Report from the Childhood Cancer Survivor Study (CCSS)

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5474122/

Magnesium Studies

http://centerhealingarts.com/treatment-programs/iv-therapy-nutrition-chelation/magnesium-studies/

On the Growth Rates of Human Malignant Tumors: Implications for Medical Decision Making

https://pubmed.ncbi.nlm.nih.gov/9274795/

Orthomolecular Oncology Review: Ascorbic Acid and Cancer 25 Years Later

https://pubmed.ncbi.nlm.nih.gov/15695476/

Oxidative Stress and Hyper-Inflammation as Major Drivers of Severe COVID-19 and Long COVID: Implications for the Benefit of High-Dose Intravenous Vitamin C

https://www.frontiersin.org/articles/10.3389/fphar.2022.899198/full

Palliative Vitamin C Application in Patients with Radiotherapy-Resistant Bone Metastases: A Retrospective Study

https://pubmed.ncbi.nlm.nih.gov/26168394/

Pharmacologic Ascorbic Acid Concentrations Selectively Kill Cancer Cells: Action as a Pro-Drug to Deliver Hydrogen Peroxide to Tissues

https://pubmed.ncbi.nlm.nih.gov/16157892/

Pharmacologic Concentrations of Ascorbate Are Achieved by Parenteral Administration and Exhibit Antitumoral Effects

https://pubmed.ncbi.nlm.nih.gov/19254759/

Pharmacological ascorbate induces cytotoxicity in prostate cancer cells through ATP depletion and induction of autophagy

https://pubmed.ncbi.nlm.nih.gov/22205155/

Pharmacological Ascorbate Radiosensitizes Pancreatic Cancer

https://pubmed.ncbi.nlm.nih.gov/26081808/#:~:text=The%20current%20study%20demonstrates%20that,nontumorigenic%20pancreatic%20ductal%20epithelial%20cells.

Pharmacological ascorbate with gemcitabine for the control of metastatic and node-positive pancreatic cancer (PACMAN): results from a phase I clinical trial

https://pubmed.ncbi.nlm.nih.gov/23381814/

Phase I clinical trial of i.v. ascorbic acid in advanced malignancy

https://pubmed.ncbi.nlm.nih.gov/18544557/

Phase I Clinical Trial to Evaluate the Safety, Tolerability, and Pharmacokinetics of High-Dose Intravenous Ascorbic Acid in Patients With Advanced Cancer

https://pubmed.ncbi.nlm.nih.gov/23670640/

Reduction in Late Mortality among 5-Year Survivors of Childhood Cancer

https://www.nejm.org/doi/full/10.1056/NEJMoa1510795

Small Cell Lung Cancer Doubling Time and its Effect on Clinical Presentation: A Concise Review

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3355865/

Systematic Review of Intravenous Ascorbate in Cancer Clinical Trials

https://pubmed.ncbi.nlm.nih.gov/30002308/

The Clinical Benefits of Perioperative Antioxidant Vitamin Therapy in Patients Undergoing Cardiac Surgery: A Meta-Analysis

https://pubmed.ncbi.nlm.nih.gov/28645181/

The Effect of Intravenous Vitamin C on Cancer- And Chemotherapy-Related Fatigue and Quality of Life

https://pubmed.ncbi.nlm.nih.gov/25360419/

The effectiveness of vitamin C in preventing and relieving the symptoms of virus-induced respiratory infections

https://pubmed.ncbi.nlm.nih.gov/10543583/

Tumor cells have decreased ability to metabolize H2O2: Implications for pharmacological ascorbate in cancer therapy

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5106370/

Vitamin C and Heart Health: A Review Based on Findings From Epidemiologic Studies

https://pubmed.ncbi.nlm.nih.gov/27529239/

Vitamin C and Immune Function

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5707683/?fbclid=IwAR3MS866UNZ8UXCmXvME2n8fGgL35S48skbHfW-6sCoC8WYV9yfNIyNSX9s

Vitamin C and Neutrophil Function: Findings from Randomized Controlled Trials

https://pubmed.ncbi.nlm.nih.gov/31487891/

Vitamin C as a Modulator of the Response to Cancer Therapy

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6384696/

Vitamin C in Complementary Oncology--Update 2009

https://pubmed.ncbi.nlm.nih.gov/19731754/

Vitamin C may reduce the duration of mechanical ventilation in critically ill patients: a meta-regression analysis

https://pubmed.ncbi.nlm.nih.gov/32047636/

Vitamin C Might Reverse Stress-induced Driver of Breast Cancer, Study Says

https://breastcancer-news.com/2019/03/18/vitamin-c-might-reverse-stress-induced-driver-of-breast-cancer-study-says/?fbclid=IwAR3WU2h-4vLDH9GLOzQ1_abkR_ZqRWZSy7NDWnbwU4smZepYiQ2O5qzRyuY

Vitamin C: Intravenous Use by Complementary and Alternative Medicine Practitioners and Adverse Effects

https://pubmed.ncbi.nlm.nih.gov/20628650/

Why high-dose vitamin C kills cancer cells

https://now.uiowa.edu/2017/01/why-high-dose-vitamin-c-kills-cancer-cells#.WdDgtdtUowU.email

Targeting Mitochondrial Stem Cell Connection in Cancer Treatment: A Hybrid Orthomolecular Approach

https://scholar.google.com/scholar?q=journal+of+orthomolecular+medicine+cancer+treatment&hl=en&as_sdt=0&as_vis=1&oi=scholart#:~:text=Targeting%20the%20Mitochondrial%2DStem%20Cell%20Connection%20in%20Cancer%20Treatment%3A%20A%20Hybrid%20Orthomolecular%20Protocol

Potential Supportive Role of IV Therapy:

IV therapy may be used as a supportive measure for individuals undergoing cancer treatment. This could involve:

Hydration: Addressing dehydration caused by certain cancer treatments or side effects.
Electrolyte Replenishment: Correcting electrolyte imbalances that can impact overall health and well-being.
High Dose Vitamin Therapy: Helping manage deficiencies, mitigating pain and side effects of conventional cancer treatments.